While most people would be happy to suddenly lose weight, unexplained weight loss that occurs without any change in diet or activity level can be a sign that something is wrong. Dieting, loss of appetite, diarrhea and some medications are all easily identifiable causes of weight loss, but if you suddenly lose 10 pounds, 5 percent of your body weight, or if your weight loss persists and you can't explain why, it's time to look at other possibilities.
Gastrointestinal Disease
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